| Protein ID |
Standard name |
Swiss-Prot annotation |
SGD annotation |
Enzymatic activity (our results) |
Structure |
Comments |
| 1. Yer037w |
PHM8 |
Phosphate metabolism protein 8 |
unknown function |
Phosphatase (XMP, CMP, UMP, GMP) |
|
PHO85 regulated (Sopko etl al., 2006) |
| 2. Ygl224c |
SSM1 |
Protein of the SSM1 family |
pyrimidine nucleotidase SDT1 |
Phosphatase (XMP, UMP, CMP) |
Yes (our) |
|
| 3. Ykl033w-a |
YKD3A |
Uncharacterized hydrolase |
unknown function |
Phosphatase (XMP, FMN, dUMP) |
|
|
| 4. Yel038w |
UTR4 |
Enolase-phosphatase E1 |
unknown function |
Phosphatase (phosphoglycolate: low activity) |
Joint Center |
Synthetic lethality with PAC10 (Ygr078c) (Tong et al., 2004) |
| 5. Ydl236w |
PHO13 |
4-Nitrophenylphosphatase |
alkaline phosphatase |
Phosphatase (phosphoglycolate) |
|
Main phosphoglycolate phosphatase (DNA repair?) |
| 6. Ykr070w |
YK50 |
Uncharacterized protein |
unknown function |
Phosphatase (glucose-6P, deoxyglucose-6P, deoxyribose-5P, glycero-1P) |
|
Localization: mitochondrion |
| 7. Ynl010w |
YNB0 |
Uncharacterized protein |
unknown function |
Phosphatase (glycero-1P) |
|
Deletion: increased glycogen accumulation (Wilson et al., 2002) |
| 8. Yer062c |
GPP2 |
Glycerol-3 phosphatase 2 |
glycerol-3 phosphatase 2 |
Phosphatase (glycero-3P, glycero-1P) |
|
Induced by hyperosmotic and oxidative stress, diauxic transition |
| 9. Yil053w |
GPP1 |
Glycerol-3 phosphatase 1 |
glycerol-3 phosphatase 1 |
Phosphatase (glycero-3P, glycero-1P) |
Yes (our) |
Constitutive isoform, induced by anaerobic and osmotic stress |
| 10. Ymr130w |
YM14 |
Uncharacterized protein |
unknown function |
Phosphatase (3P-glyceraldehyde) |
|
|
| 11. Yor131c |
YOR31 |
Uncharacterized hydrolase |
unknown function |
Phosphatase (pyridoxal phosphate) |
|
|
| 12. Ygr208w |
SERB |
Phosphoserine phosphatase |
phosphoserine phosphatase |
Phosphatase (P-serine) |
Crystals |
phosphoglycerate pathway |
| 13. Yhr044c |
DOG1 |
Deoxyglucose-6P phosphatase 1 |
deoxyglucose-6P phosphatase |
Phosphatase (deoxyglucose-6P, ribose-5P, mannose-6P, glucose-6P) |
|
resistance to 2-deoxyglucose |
| 14. Yhr043c |
DOG2 |
Deoxyglucose-6P phosphatase 2 |
deoxyglucose-6P phosphatase |
Phosphatase (deoxyglucose-6P, fructose-1P, mannose-6P, glucose-6P) |
|
Induced by oxidative and osmotic stress, resistance to 2-deoxyglucose |
| 15. Yor111w |
YOR111 |
Uncharacterized protein |
unknown function |
Nucleotide pyrophosphatase (TTP, UTP, CTP) (Maf-like!) |
|
Two-hybrid: interacts with Ent3p (Uetz et al., 2000) in Tim Hughes review (2007) |
| 16. Ybr252w |
DUT1 |
dUTP pyrophosphatase |
dUTPase |
Nucleotide pyrophosphatase (dUTP, dITP) |
solved |
Inviable; interacts with Tem1p, Cks1p, apn1, apn2, rad1, ung1, rad14, rev3, and Davierwala et al., 2005: rfc5, srb6 |
| 17. Yor004w |
UTP23 |
rRNA-processing protein UTP23 |
Processome component (40S) |
Ribonuclease (ssRNA) |
|
Inviable; interacts with: Irp1 and nop1 (Davierwala et al., 2005); Mpp10p (Bleichert et al., 2006) |
| 18. Yol042w |
NGL1 |
RNA exonuclease NGL1 |
putative endonuclease |
Ribonuclease (ssRNA endonuclease) |
|
Localization: mitochondrion |
| 19. Yml118w |
NGL3 |
Probable RNA exonuclease NGL3 |
putative endonuclease |
Ribonuclease (ssRNA endonuclease) |
|
Interacts with: Ptk2p, Tpk1p, and Tpk2p (Ptacek et al. 2005) |
| 20. Yjr019c |
TES1 |
acyl-CoA thioesterase |
acyl-CoA thioesterase |
Acyl-CoA thioesterase (lauroyl-CoA, hexanoyl-CoA, methylmalonyl-CoA) |
|
Peroxisome; interacts with Atg1p, Snf1p, and Yck1p (Ptacek et al., 2005) |
| 21. Ygr203w |
|
(Rhodanese-like) |
|
Protein phosphatase |
solved |
|
| 22. Yor285w |
|
(Rhodanese-like) |
|
Thiesterase |
solved |
|
| 23. Yil113w |
YIL3 |
probable P-Tyr phosphatase |
|
phosphatase (pNPP) |
|
|
| 24. Ydl230w |
PTP1 |
protein Tyr-phosphatase PTP1 |
|
phosphatase (pNPP, P-Tyr peptides) |
|
|
| 25. Yir026c |
PVH1 |
protein Tyr-phosphatase PVH1 |
|
phosphatase (pNPP) |
|
|
| 26. Ygr123c |
PPT1 |
protein Ser/Thr phosphatase PPT1 |
|
phosphatase (pNPP) |
|
|
| 27. Yfr028c |
CDC14 |
protein Tyr-phosphatase CDC14 |
|
phosphatase (pNPP, P-Ser peptides) |
|
|
| 28. Ybl019w |
APN2 |
apurinic endonuclease APN2 |
|
phosphodiesterase (bis-pNPP) |
|
|
| 29. Ycr036w |
RBSK |
probable ribokinase |
|
ribokinase (ribose, deoxyribose, ribulose) |
|
|
| 30. Ylr022c |
SDO1 |
ribosome maturation protein SDO1 |
|
Ribonuclease (ssRNA) |
|
|
| 31. Ykr043c |
YK23 |
Uncharacterized protein |
|
phosphatase (acid phosphatase, Fructose 1,6-diP) |
solved |
|
| 32. Yor283w |
YO283 |
probable phosphoglycerate mutase |
unknown function |
phosphatase (many substrates |
|
|
